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HIV-1 Ribonuclease H Inhibitory Phenolic Glycosides from Eugenia hyemalis

Three new galloyl arbutins, hyemalosides A–C (1–3), along with nine known compounds were isolated from the evergreen tree Eugenia hyemalis. The structures of compounds 1–3 were determined by analysis of NMR and MS data. Compounds 1–3 inhibited HIV-1 RNase H in vitro with IC(50) values of 1.46, >1...

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Detalhes bibliográficos
Main Authors: Bokesch, Heidi R., Wamiru, Antony, Le Grice, Stuart F. J., Beutler, John A., McKee, Tawnya C., McMahon, James B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586124/
https://ncbi.nlm.nih.gov/pubmed/18763827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/np8002518
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