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Estimating Kinetic and Thermodynamic Parameters from Single Molecule Enzyme-Inhibitor Interactions
We report the application of recently developed microscopic models to estimate the apparent kinetic and thermodynamic parameters in a single molecule force spectroscopy study of the carbonic anhydrase enzyme and a complementary sulfonamide inhibitor. The most probable rupture force for the enzyme-in...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2586077/ https://ncbi.nlm.nih.gov/pubmed/18808161 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/la801477a |
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