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Synthesis and Receptor Binding Properties of 2β-Alkynyl and 2β-(1,2,3-Triazol)substituted 3β-(substituted phenyl)tropane Derivatives

A series of 2β-alkynyl and 2β-(1,2,3-triazol)substituted 3β-(substituted phenyl)tropanes were synthesized and evaluated for affinities at dopamine, serotonin and norepinephrine membrane transporters using competitive radioligand binding assays. All tested compounds were found to exhibit nanomolar or...

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Autors principals: Jin, Chunyang, Navarro, Hernán A., Carroll, F. Ivy
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2585981/
https://ncbi.nlm.nih.gov/pubmed/18434164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2008.04.008
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