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Studies on Taxol Biosynthesis: Preparation of Taxadiene-diol- and triol-Derivatives by Deoxygenation of Taxusin

The putative taxol biosynthesis metabolites, taxa-4(20),11(12)-diene-5α, 13α -diol (7), taxa-4(20),11(12)-diene-5α, 9α, 13α-triol (9), and taxa-4(20),11(12)-diene-5α, 10β, 13α-triol (10), have been prepared by Barton deoxygenation of the C-9 and C10-hydroxyl groups of protected derivatives of taxusi...

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Autori principali: Li, Hui, Horiguchi, Tohru, Croteau, Rodney, Williams, Robert M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2585798/
https://ncbi.nlm.nih.gov/pubmed/19122848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2008.04.008
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