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An open form of syntaxin bypasses the requirement for UNC-13 in vesicle priming

The priming step of synaptic vesicle exocytosis is thought to require the formation of the SNARE complex, which comprises the proteins synaptobrevin, SNAP-25 and syntaxin1–3. In solution syntaxin adopts a default, closed configuration that is incompatible with formation of the SNARE complex4. Specif...

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Autors principals: Richmond, Janet E., Weimer, Robby M., Jorgensen, Erik M.
Format: Artigo
Idioma:Inglês
Publicat: 2001
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2585764/
https://ncbi.nlm.nih.gov/pubmed/11460165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/35085583
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