Role of hMOF-dependent histone H4 lysine 16 acetylation in the maintenance of TMS1/ASC gene activity

Epigenetic silencing of tumor suppressor genes in human cancers is associated with aberrant methylation of promoter region CpG islands and local alterations in histone modifications. However, the mechanisms that drive these events remain unclear. Here, we establish an important role for histone H4 l...

Full description

Saved in:
Bibliographic Details
Main Authors: Kapoor-Vazirani, Priya, Kagey, Jacob D., Powell, Doris R., Vertino, Paula M.
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2585755/
https://ncbi.nlm.nih.gov/pubmed/18701507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-0141
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items