Functional Effects of KCNE3 Mutation and its Role in the Development of Brugada Syndrome

INTRODUCTION: The Brugada Syndrome (BrS), an inherited syndrome associated with a high incidence of sudden cardiac arrest, has been linked to mutations in four different genes leading to a loss of function in sodium and calcium channel activity. Although the transient outward current (I(to)) is thou...

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Main Authors: Delpón, Eva, Cordeiro, Jonathan M, Núñez, Lucía, Thomsen, Poul Erik Bloch, Guerchicoff, Alejandra, Pollevick, Guido D., Wu, Yuesheng, Kanters, Jørgen K., Larsen, Carsten Toftager, Burashnikov, Elena, Christiansen, Michael, Antzelevitch, Charles
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2585750/
https://ncbi.nlm.nih.gov/pubmed/19122847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCEP.107.748103
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