Gain of function in I(Ks) secondary to a mutation in KCNE5 associated with atrial fibrillation

BACKGROUND: Atrial fibrillation (AF) is the most common clinical arrhythmia and a major cause of cardiovascular morbidity and mortality. Among the gene defects previously associated with AF is a gain of function of the slowly activating delayed rectifier potassium current I(Ks), secondary to mutatio...

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Autori principali: Ravn, Lasse S., Aizawa, Yoshiyasu, Pollevick, Guido D., Hofman-Bang, Jacob, Cordeiro, Jonathan M., Dixen, Ulrik, Jensen, Gorm, Wu, Yuesheng, Burashnikov, Elena, Haunso, Stig, Guerchicoff, Alejandra, Hu, Dan, Svendsen, Jesper H., Christiansen, Michael, Antzelevitch, Charles
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2515863/
https://ncbi.nlm.nih.gov/pubmed/18313602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.hrthm.2007.12.019
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