Glycogen Synthase Kinase 3 inhibition Induces Glioma Cell Death through c-MYC, NF-κB and Glucose Regulation

Glycogen synthase kinase-3 (GSK3), a serine/threonine kinase, is involved in diverse cellular processes ranging from nutrient and energy homeostasis to proliferation and apoptosis. Its role in glioblastoma multiforme (GBM) has yet to be elucidated. We identified GSK3 as a regulator of GBM cell survi...

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Bibliografiset tiedot
Päätekijät: Kotliarova, Svetlana, Pastorino, Sandra, Kovell, Lara C., Kotliarov, Yuri, Song, Hua, Zhang, Wei, Bailey, Rolanda, Maric, Dragan, Zenklusen, Jean Claude, Lee, Jeongwu, Fine, Howard A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2008
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2585745/
https://ncbi.nlm.nih.gov/pubmed/18701488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-0850
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