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Selective Modulation of Promoter Recruitment and Transcriptional Activity of PPARγ

Peroxisome proliferator-activated receptor gamma (PPARγ) is a nuclear receptor regulated by the insulin-sensitizing thiazolidinediones (TZDs). We studied selective modulation of endogenous genes by PPARγ ligands using microarray, RNA expression kinetics, and chromatin immunoprecipitation (ChIP) in 3...

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Bibliographic Details
Main Authors: Sears, Dorothy D., Hsiao, Albert, Ofrecio, Jachelle M., Chapman, Justin, He, Weimin, Olefsky, Jerrold M.
Format: Artigo
Language:Inglês
Published: 2007
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2585742/
https://ncbi.nlm.nih.gov/pubmed/17963725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2007.10.057
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