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High-dose statin use does not impair aerobic capacity or skeletal muscle function in older adults
3-Hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors (statins) are lipid-lowering agents widely employed for atherosclerosis prevention. HMG-CoA reductase blockade reduces skeletal muscle coenzyme Q(10) (CoQ(10)) levels and mitochondrial respiratory chain activities and may produce m...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Springer Netherlands
2008
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2585641/ https://ncbi.nlm.nih.gov/pubmed/19424852 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-008-9070-3 |
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