TRANSMEMBRANE SEGMENT PEPTIDES CAN DISRUPT CHOLECYSTOKININ RECEPTOR OLIGOMERIZATION WITHOUT AFFECTING RECEPTOR FUNCTION

Oligomerization of the G protein-coupled cholecystokinin (CCK) receptor has been demonstrated, but its molecular basis and functional importance are not clear. We now examine contributions of transmembrane (TM) segments to oligomerization of this receptor using a peptide competitive inhibition strat...

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Detalhes bibliográficos
Main Authors: Harikumar, Kaleeckal G., Dong, Maoqing, Cheng, Zhijie, Pinon, Delia I., Lybrand, Terry P., Miller, Laurence J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2585497/
https://ncbi.nlm.nih.gov/pubmed/17144663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi061107n
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