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DIRECT INTERACTIONS BETWEEN C. ELEGANS RAB-3 AND RIM PROVIDE A MECHANISM TO TARGET VESICLES TO THE PRESYNAPTIC DENSITY
Rim is a multi-domain, active zone protein that regulates exocytosis and is implicated in vesicle priming and presynaptic plasticity. We recently demonstrated that synaptic defects associated with loss of C. elegans Rim (termed UNC-10) are accompanied by a reduction in docked vesicles adjacent to th...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2585374/ https://ncbi.nlm.nih.gov/pubmed/18721860 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2008.08.026 |
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