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Synthesis and immunological properties of conjugates composed of group B streptococcus type III capsular polysaccharide covalently bound to tetanus toxoid.

A synthetic scheme for covalently binding group B streptococcus type III to tetanus toxoid (TT), using adipic acid dihydrazide as a spacer, is described. Type III alone or as a conjugate with TT was injected subcutaneously into laboratory mice, and the type-specific and TT antibody responses elicite...

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Bibliografiske detaljer
Udgivet i:Infect Immun
Principais autores: Lagergard, T, Shiloach, J, Robbins, J B, Schneerson, R
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1990
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC258520/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2407652/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.58.3.687-694.1990
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