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p16 Mutation Spectrum in the Premalignant Condition Barrett's Esophagus
BACKGROUND: Mutation, promoter hypermethylation and loss of heterozygosity involving the tumor suppressor gene p16 (CDKN2a/INK4a) have been detected in a wide variety of human cancers, but much less is known concerning the frequency and spectrum of p16 mutations in premalignant conditions. METHODS A...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2585012/ https://ncbi.nlm.nih.gov/pubmed/19043591 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003809 |
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