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Impact of overexpression of metallothionein-1 on cell cycle progression and zinc toxicity

Metallothioneins (MTs) have an important role in zinc homeostasis and may counteract the impact of oversupply. Both intracellular zinc and MT expression have been implicated in proliferation control and resistance to cellular stress, although the interdependency is unclear. The study addresses the c...

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Detalhes bibliográficos
Main Authors: Smith, Paul J., Wiltshire, Marie, Furon, Emeline, Beattie, John H., Errington, Rachel J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2585003/
https://ncbi.nlm.nih.gov/pubmed/18815222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00342.2008
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