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Impact of overexpression of metallothionein-1 on cell cycle progression and zinc toxicity

Metallothioneins (MTs) have an important role in zinc homeostasis and may counteract the impact of oversupply. Both intracellular zinc and MT expression have been implicated in proliferation control and resistance to cellular stress, although the interdependency is unclear. The study addresses the c...

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Détails bibliographiques
Auteurs principaux: Smith, Paul J., Wiltshire, Marie, Furon, Emeline, Beattie, John H., Errington, Rachel J.
Format: Artigo
Langue:Inglês
Publié: American Physiological Society 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2585003/
https://ncbi.nlm.nih.gov/pubmed/18815222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00342.2008
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