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Novel molecular insights into RhoA GTPase-induced resistance to aqueous humor outflow through the trabecular meshwork

Impaired drainage of aqueous humor through the trabecular meshwork (TM) culminating in increased intraocular pressure is a major risk factor for glaucoma, a leading cause of blindness worldwide. Regulation of aqueous humor drainage through the TM, however, is poorly understood. The role of RhoA GTPa...

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Библиографические подробности
Главные авторы: Zhang, Min, Maddala, Rupalatha, Rao, Ponugoti Vasantha
Формат: Artigo
Язык:Inglês
Опубликовано: American Physiological Society 2008
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2584993/
https://ncbi.nlm.nih.gov/pubmed/18799648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00481.2007
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