Stimulation of β3-adrenoceptors relaxes rat urinary bladder smooth muscle via activation of the large-conductance Ca(2+)-activated K(+) channels

We investigated the role of large-conductance Ca(2+)-activated K(+) (BK) channels in β3-adrenoceptor (β3-AR)-induced relaxation in rat urinary bladder smooth muscle (UBSM). BRL 37344, a specific β3-AR agonist, inhibits spontaneous contractions of isolated UBSM strips. SR59230A, a specific β3-AR anta...

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Detalhes bibliográficos
Main Authors: Hristov, Kiril L., Cui, Xiangli, Brown, Sean M., Liu, Lei, Kellett, Whitney F., Petkov, Georgi V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2008
Assuntos:
Receptors and Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2584988/
https://ncbi.nlm.nih.gov/pubmed/18799656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00001.2008
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