Age-dependent FOXO regulation of p27(Kip1) expression via a conserved binding motif in rat muscle precursor cells

Previously, we have demonstrated that forkhead box O3a (FOXO3a) overexpression increased p27(Kip1) promoter activity and protein expression, whereas it decreased proliferation in muscle precursor cells (MPCs). The objectives of the present study were to 1) locate and identify FOXO regulatory element...

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Bibliographische Detailangaben
Hauptverfasser: Lees, Simon J., Childs, Tom E., Booth, Frank W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2008
Schlagworte:
Muscle Cell Biology and Cell Motility
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2584982/
https://ncbi.nlm.nih.gov/pubmed/18787071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00349.2008
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