IGF-I activates the mouse type IIb myosin heavy chain gene

IGF-I increases skeletal muscle mass, but whether IGF-I increases type IIb myosin heavy chain (MyHC) transcriptional activity is not known. C(2)C(12) myotubes were cultured with or without IGF-I to determine whether IGF-I increases type IIb MyHC promoter activity, and if so, what region of the promo...

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Detalhes bibliográficos
Main Authors: Shanely, R. Andrew, Zwetsloot, Kevin A., Childs, Thomas E., Lees, Simon J., Tsika, Richard W., Booth, Frank W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2009
Assuntos:
Muscle Cell Biology and Cell Motility
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2770749/
https://ncbi.nlm.nih.gov/pubmed/19657059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00169.2009
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