Glucagon receptor recycling: role of carboxyl terminus, β-arrestins, and cytoskeleton

Glucagon receptor (GR) activity and expression are altered in several diseases, including Type 2 diabetes. Previously, we investigated the mechanism of GR desensitization and internalization. The present study focused on the fate of internalized GR. Using both hamster hepatocytes and human embryonic...

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Autores principales: Krilov, Lada, Nguyen, Amy, Miyazaki, Teruo, Unson, Cecilia G., Bouscarel, Bernard
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2008
Materias:
Receptors and Signal Transduction
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2584980/
https://ncbi.nlm.nih.gov/pubmed/18787074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00240.2008
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