Aberrant methylation of the Adenomatous Polyposis Coli (APC) gene promoter is associated with the inflammatory breast cancer phenotype

Aberrant methylation of the adenomatous polyposis coli (APC) gene promoter occurs in about 40% of breast tumours and has been correlated with reduced APC protein levels. To what extent epigenetic alterations of the APC gene may differ according to specific breast cancer phenotypes, remains to be elu...

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Autores principales: Van der Auwera, I, Van Laere, S J, Van den Bosch, S M, Van den Eynden, G G, Trinh, B X, van Dam, P A, Colpaert, C G, van Engeland, M, Van Marck, E A, Vermeulen, P B, Dirix, L Y
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2008
Materias:
Genetics and Genomics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2584952/
https://ncbi.nlm.nih.gov/pubmed/18841156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604705
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