Effects of G/A polymorphism, rs266882, in the androgen response element 1 of the PSA gene on prostate cancer risk, survival and circulating PSA levels

Prostate-specific antigen (PSA) is a protease produced in the prostate that cleaves insulin-like growth factor binding protein-3 and other proteins. Production is mediated by the androgen receptor (AR) binding to the androgen response elements (ARE) in the promoter region of the PSA gene. Studies of...

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Detalhes bibliográficos
Main Authors: Jesser, C, Mucci, L, Farmer, D, Moon, C, Li, H, Gaziano, J M, Stampfer, M, Ma, J, Kantoff, P
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Genetics and Genomics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2584945/
https://ncbi.nlm.nih.gov/pubmed/18827812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604690
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