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The insecticide fipronil and its metabolite fipronil sulphone inhibit the rat α1β2γ2L GABA(A) receptor

BACKGROUND AND PURPOSE: Fipronil is the active ingredient in a number of widely used insecticides. Human exposure to fipronil leads to symptoms (headache, nausea and seizures) typically associated with the antagonism of GABA(A) receptors in the brain. In this study, we have examined the modulation o...

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Detalhes bibliográficos
Main Authors: Li, P, Akk, G
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2584928/
https://ncbi.nlm.nih.gov/pubmed/18660823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.309
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