Antinociceptive effects of tetrazole inhibitors of endocannabinoid inactivation: cannabinoid and non-cannabinoid receptor-mediated mechanisms

BACKGROUND AND PURPOSE: Tetrazoles were recently developed as inhibitors of the cellular uptake of the endocannabinoid anandamide or of its hydrolysis by fatty acid amide hydrolase (FAAH), but were proposed to act also on non-endocannabinoid-related serine hydrolases. EXPERIMENTAL APPROACH: We teste...

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Detalhes bibliográficos
Main Authors: Maione, S, Morera, E, Marabese, I, Ligresti, A, Luongo, L, Ortar, G, Di Marzo, V
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2584918/
https://ncbi.nlm.nih.gov/pubmed/18660824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.308
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