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Lubiprostone activates non-CFTR-dependent respiratory epithelial chloride secretion in cystic fibrosis mice
Periciliary fluid balance is maintained by the coordination of sodium and chloride channels in the apical membranes of the airways. In the absence of the cystic fibrosis transmembrane regulator (CFTR), chloride secretion is diminished and sodium reabsorption exaggerated. ClC-2, a pH- and voltage-dep...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Physiological Society
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2584880/ https://ncbi.nlm.nih.gov/pubmed/18805957 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.90221.2008 |
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