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Extracellular nucleotides stimulate Cl(−) currents in biliary epithelia through receptor-mediated IP3 and Ca(2+) release

Extracellular ATP regulates bile formation by binding to P2 receptors on cholangiocytes and stimulating transepithelial Cl(−) secretion. However, the specific signaling pathways linking receptor binding to Cl(−) channel activation are not known. Consequently, the aim of these studies in human Mz-Cha...

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Detalhes bibliográficos
Main Authors: Dutta, Amal K., Woo, Kangmee, Doctor, R. Brian, Fitz, J. Gregory, Feranchak, Andrew P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2584822/
https://ncbi.nlm.nih.gov/pubmed/18787062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.90382.2008
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