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The crystal structure of avian CD1 reveals a smaller, more primordial antigen-binding pocket compared to mammalian CD1

The molecular details of glycolipid presentation by CD1 antigen-presenting molecules are well studied in mammalian systems. However, little is known about how these non-classical MHC class I (MHCI) molecules diverged from the MHC locus to create a more complex, hydrophobic binding groove that binds...

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Detalhes bibliográficos
Main Authors: Zajonc, Dirk M., Striegl, Harald, Dascher, Christopher C., Wilson, Ian A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2584731/
https://ncbi.nlm.nih.gov/pubmed/19004781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0809814105
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