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Mitomycin C-treated dendritic cells inactivate autoreactive T cells: Toward the development of a tolerogenic vaccine in autoimmune diseases

Treatment of autoimmune diseases remains a challenge for immunological research. An ideal therapy should inhibit the immune reaction against the diseased organ and leave the rest of the immune response intact. Our previous studies showed that donor-derived dendritic cells (DCs) treated in vitro with...

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Detalhes bibliográficos
Main Authors: Terness, Peter, Oelert, Thilo, Ehser, Sandra, Chuang, Jing Jing, Lahdou, Imad, Kleist, Christian, Velten, Florian, Hämmerling, Günter J., Arnold, Bernd, Opelz, Gerhard
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2584573/
https://ncbi.nlm.nih.gov/pubmed/19017789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0807185105
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