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Intersection of the RNAi and X-inactivation pathways
In mammals, dosage compensation is achieved by X-chromosome inactivation (XCI) in the female. The noncoding Xist gene initiates silencing of the X, while its antisense partner Tsix blocks silencing. The complementarity of Xist and Tsix RNAs has long suggested a role for RNAi. Here, we report that mu...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2584363/ https://ncbi.nlm.nih.gov/pubmed/18535243 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1157676 |
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