Myogenic stem cell function is impaired in mice lacking the forkhead/winged helix protein MNF

Myocyte nuclear factor (MNF) is a winged helix transcription factor that is expressed selectively in myogenic stem cells (satellite cells) of adult animals. Using a gene knockout strategy to generate a functional null allele at the Mnf locus, we observed that mice lacking MNF are viable, but severel...

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Huvudupphovsmän: Garry, Daniel J., Meeson, Annette, Elterman, Joel, Zhao, Yuhe, Yang, Peng, Bassel-Duby, Rhonda, Williams, R. Sanders
Materialtyp: Artigo
Språk:Inglês
Publicerad: The National Academy of Sciences 2000
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC25843/
https://ncbi.nlm.nih.gov/pubmed/10792059
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