Myogenic stem cell function is impaired in mice lacking the forkhead/winged helix protein MNF

Myocyte nuclear factor (MNF) is a winged helix transcription factor that is expressed selectively in myogenic stem cells (satellite cells) of adult animals. Using a gene knockout strategy to generate a functional null allele at the Mnf locus, we observed that mice lacking MNF are viable, but severel...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Garry, Daniel J., Meeson, Annette, Elterman, Joel, Zhao, Yuhe, Yang, Peng, Bassel-Duby, Rhonda, Williams, R. Sanders
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2000
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC25843/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10792059/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.100501197
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