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Peptidyl Molecular Imaging Contrast Agents Using a New Solid Phase Peptide Synthesis Approach

A versatile method is disclosed for solid phase peptide synthesis (SPPS) of molecular imaging contrast agents. A DO3A moiety was derivatized to introduce a CBZ-protected amino group and then coupled to a polymeric support. CBZ cleavage with Et(2)AlCl/thioanisole was optimized for SPPS. Amino acids w...

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Dettagli Bibliografici
Autori principali: Yoo, Byunghee, Pagel, Mark D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2584118/
https://ncbi.nlm.nih.gov/pubmed/17330953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc060250q
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