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An amine-derivatized, DOTA-loaded polymeric support for Fmoc Solid Phase Peptide Synthesis

An amine-derivatized DOTA has been used to modify the surface of a polymeric support for conventional Solid Phase Peptide Synthesis (SPPS) following standard Fmoc chemistry methods. This methodology was used to synthesize a peptide-DOTA conjugate that was demonstrated to be a PARACEST MRI contrast a...

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Detalhes bibliográficos
Main Authors: Yoo, Byunghee, Sheth, Vipul R., Pagel, Mark D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2702766/
https://ncbi.nlm.nih.gov/pubmed/20161272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2009.05.061
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