Protection against experimental pseudomembranous colitis in gnotobiotic mice by use of monoclonal antibodies against Clostridium difficile toxin A.

The pathogenicity of Clostridium difficile is due to the production of two toxins (toxins A and B). We prepared monoclonal antibodies against toxin A and determined whether axenic mice passively immunized with the monoclonal antibodies were protected against C. difficile disease. The mice were kept...

Täydet tiedot

Bibliografiset tiedot

Julkaisussa:	Infect Immun
Päätekijät:	Corthier, G, Muller, M C, Wilkins, T D, Lyerly, D, L'Haridon, R
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	American Society for Microbiology (ASM) 1991
Aiheet:	Research Article
Linkit:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC258389/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1900059/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.59.3.1192-1195.1991
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