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An interleukin-1 receptor antagonist blocks lipopolysaccharide-induced colony-stimulating factor production and early endotoxin tolerance.

In this report, administration of a recombinant interleukin-1 receptor antagonist protein to mice was found to inhibit induction of colony-stimulating factor as well as induction of early endotoxin tolerance by lipopolysaccharide. These findings provide direct evidence that interleukin-1 is an inter...

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Bibliographic Details
Published in:Infect Immun
Main Authors: Henricson, B E, Neta, R, Vogel, S N
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1991
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC258388/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1825485/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.59.3.1188-1191.1991
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