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Clearance of Adenovirus by Kupffer Cells Is Mediated by Scavenger Receptors, Natural Antibodies, and Complement

Kupffer cells (KCs) rapidly remove intravenously injected adenovirus (Ad) vectors from the circulation. A better understanding of the mechanisms involved could suggest strategies to improve Ad gene delivery by suppressing or evading KC uptake. We recently showed that clearance of Ad type 5 vectors b...

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Bibliografski detalji
Glavni autori: Xu, Zhili, Tian, Jie, Smith, Jeffrey S., Byrnes, Andrew P.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2583672/
https://ncbi.nlm.nih.gov/pubmed/18815305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01320-08
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