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Estimating In Vivo Death Rates of Targets due to CD8 T-Cell-Mediated Killing

Despite recent advances in immunology, several key parameters determining virus dynamics in infected hosts remain largely unknown. For example, the rate at which specific effector and memory CD8 T cells clear virus-infected cells in vivo is hardly known for any viral infection. We propose a framewor...

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Detalhes bibliográficos
Main Authors: Ganusov, Vitaly V., De Boer, Rob J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2583656/
https://ncbi.nlm.nih.gov/pubmed/18815293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01128-08
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