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Murine Coronaviruses Encoding nsp2 at Different Genomic Loci Have Altered Replication, Protein Expression, and Localization

Partial or complete deletion of several coronavirus nonstructural proteins (nsps), including open reading frame 1a (ORF1a)-encoded nsp2, results in viable mutant proteins with specific replication defects. It is not known whether expression of nsps from alternate locations in the genome can compleme...

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Détails bibliographiques
Auteurs principaux: Gadlage, Mark J., Graham, Rachel L., Denison, Mark R.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2583644/
https://ncbi.nlm.nih.gov/pubmed/18815297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01126-07
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