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Antibodies to Capsular Polysaccharide and Clumping Factor A Prevent Mastitis and the Emergence of Unencapsulated and Small-Colony Variants of Staphylococcus aureus in Mice

The pathogenesis of Staphylococcus aureus infections is influenced by multiple virulence factors that are expressed under variable conditions, and this has complicated the design of an effective vaccine. Clinical trials that targeted the capsule or clumping factor A (ClfA) failed to protect the reci...

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Hlavní autoři: Tuchscherr, Lorena P. N., Buzzola, Fernanda R., Alvarez, Lucía P., Lee, Jean C., Sordelli, Daniel O.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2583566/
https://ncbi.nlm.nih.gov/pubmed/18809660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00874-08
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