African Trypanosomes Contain 5-Methylcytosine in Nuclear DNA

It is currently unclear if there are modified DNA bases in Trypanosoma brucei other than J-base. We identify herein a cytosine-5 DNA methyltransferase gene and report the presence and location of 5-methylcytosine in genomic DNA. Our data demonstrate that African trypanosomes contain a functional cyt...

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Main Authors: Militello, Kevin T., Wang, Ping, Jayakar, Sangeeta K., Pietrasik, Rebecca L., Dupont, Christopher D., Dodd, Kristi, King, Anthony M., Valenti, Paul R.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology (ASM) 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2583544/
https://ncbi.nlm.nih.gov/pubmed/18791035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00198-08
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