Potentially Exposed but Uninfected Individuals Produce Cytotoxic and Polyfunctional Human Immunodeficiency Virus Type 1-Specific CD8(+) T-Cell Responses Which Can Be Defined to the Epitope Level

We measured CD8(+) T-cell responses in 12 potentially exposed but uninfected men who have sex with men by using cytokine flow cytometry. Four of the individuals screened exhibited polyfunctional immune responses to human immunodeficiency virus type 1 Gag or Vif. The minimum cytotoxic T lymphocyte ep...

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Detalhes bibliográficos
Main Authors: Erickson, A. L., Willberg, C. B., McMahan, V., Liu, A., Buchbinder, S. P., Grohskopf, L. A., Grant, R. M., Nixon, D. F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Immune Mechanisms
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2583520/
https://ncbi.nlm.nih.gov/pubmed/18815234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00247-08
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