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Biosynthesis of Ubiquinone Compounds with Conjugated Prenyl Side Chains

Enzymatic steps from two different biosynthetic pathways were combined in Escherichia coli, directing the synthesis of a new class of biomolecules—ubiquinones with prenyl side chains containing conjugated double bonds. This was achieved by the activity of a C(30) carotenoid desaturase, CrtN, from St...

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Main Authors: Lee, Pyung Cheon, Salomon, Christine, Mijts, Benjamin, Schmidt-Dannert, Claudia
格式: Artigo
語言:Inglês
出版: American Society for Microbiology (ASM) 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2583475/
https://ncbi.nlm.nih.gov/pubmed/18820051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.01495-08
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