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Midazolam administration reverses thermal hyperalgesia and prevents GABA transporter loss in a rodent model of neuropathic pain
BACKGROUND: Loss of GABA inhibition in the spinal dorsal horn may contribute to neuropathic pain. Here we examined whether systemic administration of the benzodiazepine midazolam would alleviate thermal hyperalgesia due to chronic constriction injury (CCI) of the sciatic nerve. METHODS: Hyperalgesia...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2583451/ https://ncbi.nlm.nih.gov/pubmed/18349209 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1213/ane.0b013e318164f1e9 |
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