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Structure/Function Analysis of the Interaction of Phosphatidylinositol 4,5-Bisphosphate with Actin-capping Protein: IMPLICATIONS FOR HOW CAPPING PROTEIN BINDS THE ACTIN FILAMENT

The heterodimeric actin-capping protein (CP) can be inhibited by polyphosphoinositides, which may be important for actin polymerization at membranes in cells. Here, we have identified a conserved set of basic residues on the surface of CP that are important for the interaction with phosphatidylinosi...

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Detalles Bibliográficos
Main Authors: Kim, Kyoungtae, McCully, Michelle E., Bhattacharya, Nandini, Butler, Boyd, Sept, David, Cooper, John A.
Formato: Artigo
Idioma:Inglês
Publicado: 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2583367/
https://ncbi.nlm.nih.gov/pubmed/17182619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M609850200
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