A Phase II Study of Gefitinib, 5-Fluorouracil, Leucovorin, and Oxaliplatin (IFOX) in Previously Untreated Patients with Metastatic Colorectal Cancer

PURPOSE: To investigate the IFOX regimen (gefitinib, 5-fluorouracil [5-FU], leucovorin and oxaliplatin) as first-line therapy in patients with metastatic colorectal cancer. EXPERIMENTAL DESIGN: Eligible patients had stage IV colorectal adenocarcinoma, and had not received prior chemotherapy for meta...

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Detalhes bibliográficos
Main Authors: Fisher, George A., Kuo, Timothy, Ramsey, Meghan, Schwartz, Erich, Rouse, Robert V., Cho, Cheryl D., Halsey, Joanne, Sikic, Branimir I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2583341/
https://ncbi.nlm.nih.gov/pubmed/18981005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-1014
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