In Vivo and in Vitro Studies of a Functional Peroxisome Proliferator-activated Receptor γ Response Element in the Mouse pdx-1 Promoter

We reported that peroxisome proliferator-activated receptor γ (PPARγ) transcriptionally regulates the β-cell differentiation factor pancreatic duodenal homeobox (PDX)-1 based on in vitro RNA interference studies. We have now studied mice depleted of PPARγ within the pancreas (PANC PPARγ(-/-)) create...

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Bibliographische Detailangaben
Hauptverfasser: Gupta, Dhananjay, Jetton, Thomas L., Mortensen, Richard M., Duan, Sheng Zhong, Peshavaria, Mina, Leahy, Jack L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2008
Schlagworte:
Transcription, Chromatin, and Epigenetics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2583321/
https://ncbi.nlm.nih.gov/pubmed/18718916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M801813200
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