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Follistatin-like 1, a Secreted Muscle Protein, Promotes Endothelial Cell Function and Revascularization in Ischemic Tissue through a Nitric-oxide Synthase-dependent Mechanism

Myogenic Akt signaling coordinates blood vessel recruitment with normal tissue growth. Here, we investigated the role of Follistatin-like 1 (Fstl1) in the regulation of endothelial cell function and blood vessel growth in muscle. Transgenic Akt1 overexpression in skeletal muscle led to myofiber grow...

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Hlavní autoři: Ouchi, Noriyuki, Oshima, Yuichi, Ohashi, Koji, Higuchi, Akiko, Ikegami, Chiaki, Izumiya, Yasuhiro, Walsh, Kenneth
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2583310/
https://ncbi.nlm.nih.gov/pubmed/18718903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M803440200
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