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Follistatin-Like 1 Is an Akt-Regulated Cardioprotective Factor That Is Secreted by the Heart

BACKGROUND: The Akt protein kinase is an important mediator of cardiac myocyte growth and survival. To identify factors with novel therapeutic applications in cardiac diseases, we focused on the identification of factors secreted from Akt1-activated cells that have cardioprotective effects through a...

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Detalhes bibliográficos
Main Authors: Oshima, Yuichi, Ouchi, Noriyuki, Sato, Kaori, Izumiya, Yasuhiro, Pimentel, David R., Walsh, Kenneth
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2679251/
https://ncbi.nlm.nih.gov/pubmed/18519848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.108.767673
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